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About the NIH Molecular Libraries Roadmap Initiative
The NCC was developed as part of the NIH Molecular Libraries Roadmap Initiative. The Molecular Libraries Roadmap offers biomedical researchers access to the large-scale compound screening technology necessary to identify small molecules that can be optimized as chemical probes to study the functions of genes, cells, and biochemical pathways. The major elements of this program are

1) A network of high throughput screening centers (the MLSCN), with a screening library of small molecules planned to contain up to 500,000 compounds,

2) A public Cheminformatics database, PubChem, to disseminate the results of the MLSCN screens (http://pubchem.ncbi.nlm.nih.gov) and

3) A series of technology development initiatives, including assay development funding programs. The NCC was established to provide compounds to investigators outside the MLSCN to further enable the use of compound screens in biomedical research. For more information about the Molecular Libraries Initiative or to sign up to receive announcements from the list serve, go to http://nihroadmap.nih.gov/molecularlibraries/.
About BioFocus DPI
BioFocus DPI, a Galapagos Company, provides compound management services at its South San Francisco site, currently home to the National Institutes of Health (NIH) Molecular Libraries Small Molecule Repository (MLSMR).

BioFocus DPI offers the following compound management services:

- Compound identification, selection, and procurement
- High throughput Compound Quality Control (QC) and purification
- Compound storage
- Compound reformatting, plating, and distribution

BioFocus DPI uses state-of-the-art equipment and processes to provide the highest level of sample integrity. Our validated modern manufacturing practices and certified Quality Management System ensure fast turnaround for screening samples in a wide range of high-throughput screening (HTS) formats.

For additional information on our compound management capabilities, please call (650) 228-1400 or email us at bd@glpg.com
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